Angiogenesis & Neovascularisation
It is well established that laser therapy can increase angiogenesis (Corazza et al 2007, Tuby et al. 2009, Vivian et al. 2013).
This increase in circulation has been demonstrated and used in wound healing for many years.
Although angiogenesis may not be desirable in every pathology it has it’s place in rehabilitation.
How does laser do this?
Vivian et al. (2013) showed different laser wave lengths did it differently
“660 nm laser at 40 J/cm2 induced angiogenesis via hypoxia inducible factor-1α (HIF-1α), followed by an increase in Vascular endothelial growth factor (VEGF), Messenger RNA (mRNA) and formation of new vessels in the tissue.
780 nm laser induced VEGF mRNA. However, we did not see any relation with increased HIF-1α.”