Dosage

Zein. Selting & Hamblin (2018) reviewed the studies on laser particularly looking at energy and power. They stated some simple principles found throughout the literature:

Different tissues can be divided into different categories for laser

  1. Higher numbers of mitochondria (muscle, inflammatory cells, nerve)
    • = Susceptible to over-dosing
  2. Lower numbers of mitochondria (skin, tendon, cartilage, bone)
    • = Less susceptible to over-dosing

“Although the results showed a high degree of variability. Ineffective studies in cells with high mitochondrial activity appeared to be more often due to over-dosing than to under-dosing.”